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10 questions you have about ALS (and the answers)

Augusta University Health on ALS

Ever heard of Amyotrophic Lateral Sclerosis (ALS)? If not, you probably have and weren’t aware that it’s most commonly called Lou Gehrig’s disease, after the famous baseball player who was diagnosed with it. ALS is a frightening and confusing disorder that leaves us with many questions about who can get ALS, the causes, and the symptoms.

Here are some of the most common questions about ALS and their answers.

  • What is ALS? Amyotrophic Lateral Sclerosis is a rare disorder that affects the function of nerves and muscles that are responsible for voluntary muscle movement. ALS is a degenerative disease that causes the death of the nerve cells that control our muscles.  It leads to progressive weakness that will spread from limb to limb to ultimately involve the entire body.
  • Who can get it? Most people develop ALS between 40-70, the older a person is, the higher your risk of developing ALS. However, it can occur as early as your 20s. ALS is 20% more common in men than women.
  • Is ALS contagious? No.
  • Is it deadly? The average life expectancy after diagnosis is about 2 to 5 years, but many people live longer than 5 years.
  • How common is it? Around 5,000 people in the United States are diagnosed with ALS per year. There is roughly a 2/100,000 chance of diagnosis.
  • Are there risk factors? There are no sure risk factors. Interestingly, military veterans are twice as likely to develop ALS.
  • What are the symptoms? Muscle twitches, muscle cramps, tight or stiff muscles, muscle weakness, slurred and nasal speech, and difficulty chewing or swallowing are all common symptoms seen in many cases of ALS.
  • What are the causes? Most cases of ALS are sporadic ALS, meaning the disease seems to occur randomly with no risk factors and no family history of ALS.
  • What kind of daily effect can ALS cause? ALS causes the diagnosed person to lose control of their voluntary muscles, which affects everyday movements such as chewing, walking, and talking.
  • Is there a cure? Right now there is no cure but there are treatments that can help control symptoms. There are medications, physical therapy, speech therapy, nutritional, and breathing support which may make living with this disease easier and more manageable.

“While we have no cure for ALS, we do have treatments that can make living with ALS better,” says  Dr. Michael H. Rivner from the Augusta University Health ALS Clinic . “The Augusta University Health ALS clinic has an active research program designed to help find better treatments for ALS. Our clinic provides the help and support for our patients to live a better life despite having a fatal neuromuscular disease.”

If you or someone you love has ALS, you know how difficult it is to be able to access the care you need to treat and manage this neurodegenerative disease. At Augusta University’s ALS Clinic, patients see their physicians and other caregivers on the same day, in the same room, and receive highly specialized neurological care that may slow the disease progression. Learn more about the clinic and meet the care team at augustahealth.org/als.

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Augusta University Health

Based in Augusta, Georgia, Augusta University Health is a world-class health care network, offering the most comprehensive primary, specialty and subspecialty care in the region. Augusta University Health provides skilled, compassionate care to its patients, conducts leading-edge clinical research and fosters the medical education and training of tomorrow’s health care practitioners. Augusta University Health is a not-for-profit corporation that manages the clinical operations associated with Augusta University.

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How Amyotrophic Lateral Sclerosis (ALS) Is Diagnosed

  • Self-Checks

Physical Examination

Labs and tests, differential diagnosis.

  • Next in Amyotrophic Lateral Sclerosis Guide How Amyotrophic Lateral Sclerosis (ALS) Is Treated

Diagnosing amyotrophic lateral sclerosis (ALS) is not straightforward. There is no single test to confirm ALS. A healthcare provider, such as a neurologist , will take a full medical history, conduct a physical exam, and order more specific muscle and imaging tests.

This article discusses the different tests and procedures used to diagnose ALS, as well as symptoms and other diseases that may be mistaken for ALS.

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ALS is a progressive disease that causes the nerve cells in the brain and spinal cord that send messages to the muscles of the body to deteriorate. It affects basic voluntary movements, such as walking, talking, and chewing.

Over time, the brain can no longer initiate or control movement. The muscles of the body atrophy , or waste away, causing more severe symptoms.

Self-Checks/At-Home Testing

There is no way to test for ALS at home. However, knowing the symptoms can help you recognize when you should to talk to a healthcare provider. Understanding the signs of ALS and knowing how they affect your body can help you communicate any changes you notice in your body’s function.

Early ALS symptoms are usually subtle, but eventually become more noticeable as the muscles weaken.

Some signs to look for in the early presentation of ALS include:

  • Muscle twitches in the arms, legs, shoulders, or tongue
  • Muscle cramps
  • Spasticity (tight and stiff muscles)
  • Muscle weakness in an arm or leg
  • Slurred speech
  • Difficulty chewing

The first signs of ALS typically appear in one arm or leg. You may notice that simple tasks such as buttoning a shirt or typing at the computer become more difficult. If your leg is affected, you may trip or stumble more often.

Though the arms and legs are typically affected first, for some, the first ALS symptoms may appear as difficulty swallowing or trouble speaking.

Tracking Symptoms

If you experience any of these symptoms, it's important to take note of how long they have been occurring and if they have progressed so that you can discuss them with your healthcare provider.

If you experience signs of ALS, your healthcare provider will likely conduct a physical examination, as well as ask questions about the history of your symptoms. They may also ask if anyone in your family has ALS or other diseases that affect the brain or spinal cord.

During the physical exam, your healthcare provider will test you for tight and stiff muscles, twitching muscles, muscle weakness, and loss of muscle mass or atrophy. They will also examine your reflexes to see if they respond faster than normal.

A provider will also look for another sign known as Babinski reflex . With this reflex, the big toe moves upward when the bottom of the foot is stroked.

This reflex typically disappears after the age of two unless there is neurological damage, like the kind that occurs with ALS.

After a physical exam, your healthcare provider may order several tests that can help with the diagnosis. Blood work will most likely be done to help exclude other causes of symptoms, such as thyroid disorders or low vitamin B12 levels.

The most common test used for suspected ALS is an electromyography (EMG). This test involves sensors and an electric current placed through a needle into the muscle that looks at the signals that run between nerves and muscles.

In ALS, there is a distinct pattern of electrical activity in the muscles and nerves. If this pattern is seen, your provider will order other tests to confirm the diagnosis.

In some cases, a muscle biopsy may also provide information that can lead to or exclude an ALS diagnosis. Genetic testing can also be performed.

Sometimes your provider may order a spinal tap (lumbar puncture), which removes a sample of fluid surrounding the spinal cord for examination in a lab.

An MRI (magnetic resonance imaging) of the brain and spinal cord can also be used in the diagnosis of ALS.

While MRI images of the brain or spinal cord are not reliable enough to diagnose ALS, they are helpful in ruling out other diseases, such as multiple sclerosis (MS) or a brain tumor .

Since there is not one specific test for ALS, diagnosing ALS is often a diagnosis of exclusion. This means that if your healthcare provider suspects you have ALS, they will conduct tests to rule out all possible causes of your symptoms before officially diagnosing you with ALS.

Other diseases that cause similar symptoms to ALS include, but are not limited to:

  • Cervical spine disease
  • Brain or spinal cord tumor
  • Vitamin B12 deficiency
  • Multiple sclerosis (potentially disabling autoimmune disease causing nerve damage between the brain and body)
  • Myasthenia gravis (autoimmune disease destroying nerve and muscle communication)
  • Lead poisoning
  • Thyroid disorders
  • Cervical spondylosis (age-related wear and tear of the neck’s spinal disks)

Testing for these other diseases and syndromes will help your healthcare provider pinpoint a precise diagnosis.

Since an ALS diagnosis is a diagnosis of exclusion, experiencing one or more of the symptoms does not necessarily mean you have ALS. However, it is important to know the signs and symptoms of the disease so that you can note them and talk to your healthcare provider about your concerns. If ALS is suspected, your provider will conduct a physical exam and order other specific tests, such as an EMG, muscle biopsy, or MRI.

A Word From Verywell

Diagnosing ALS is not always straightforward and can take some time. Experiencing symptoms of ALS will naturally cause some fear and concern. Talking to your healthcare provider about these concerns can help you work through it. If a diagnosis of ALS is confirmed, seeking the aid of a qualified mental health provider—or finding a support group in your area—can help you adjust to your life with ALS.

Receiving the news of an incurable disease is never easy, but keeping the lines of communication open with your healthcare team, friends, and family can ease some of the fear and anxiety that may come with an ALS diagnosis.

National Institute of Neurological Disorders and Stroke. Amyotrophic lateral sclerosis (ALS) fact sheet .

Zarei S, Carr K, Reiley L, et al. A comprehensive review of amyotrophic lateral sclerosis .  Surg Neurol Int . 2015;6:171. doi:10.4103/2152-7806.169561

Genetic and Rare Diseases Information Center. Amyotrophic lateral sclerosis .

Muscular Dystrophy Association. Diagnosis - amyotrophic lateral sclerosis (ALS) .

Gupta A, Nguyen TB, Chakraborty S, Bourque PR. Accuracy of Conventional MRI in ALS .  Can J Neurol Sci . 2014;41(1):53-57. doi:10.1017/s0317167100016267

GeneReviews®, Siddique N, Siddique T. Amyotrophic lateral sclerosis overview . Updated September 30, 2021.

By Cory Martin Martin is the author of seven books and a patient advocate who has written about her experiences with lupus and multiple sclerosis.

Practice Test On ALS! Quiz

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ALS in some cases refers to disease known as the Amyotrophic Lateral Sclerosis which leads to gradual paralyzes of people because the brain is no longer able to communicate with the muscle but this scenario is a different situation. This has got to do with a military stuff. Take this quiz and find out what is there.

Learning is a process that changes the way a person...

Acts, judges or maintains

Thinks, feels or behaves

Behaves, acts or produces

Feels, complains or accompishes

Rate this question:

The cognitive domain consists of

Comprehension. learning, implementation

Process, application, learning

Knowledge, comprehension, application

Understanding, recognizing, application

What are the three levels of affective learning?

Attitude, Appreciation and Receiving

Responding, Appreciation and Valuing

Valuing, Attitude and Receiving

Receiving, Responding, and Valuing

What is Bloom's Taxonomy?

Cognitive, affective, psychomotor

Incognito, inaffective, psychoactive

Knowing, feeling, wasting

Comprehension, Understanding, Psychosis

What is Cognitive thinking?

The knowledge of understanding the learning process

The comprehension of thinking

The thinking or reasoning component of the learning process

The ability to think subconsciously

What is Affective learning?

The high or low value you assign to learning

The feeling or internalization component of learning

Paying attention to what is presented

Regurgitating something you learnt

Receiving is the first level of learning. At this level, learners

Pay attention to what is being presented

Take in information they want to hear

Responding to information you receive

Accept to be taught

Responding is the second level of learning. At this level, learners

Question the information they have received.

Have some sort of action or response to what they have received.

Give feedback on what is learnt

Valuing is the third level of learning. At this level, learners

Become interested in the information given to them.

Pay attention to what is being presented to them.

May gain worth or value assigned to the concept the have learned.

Determine whether what is learnt is important for personal growth

What is the EPME Structured THinking Process?

Identify, Differentiate, Determine, and Predict

Identify, Determine, Process and Predict

Understand, Process, Differentiate, and Solve

Process, Predict, Identify, Determine

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ALS Problem Solvers

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Alternative Learning System

Anything about Alternative Learning System (ALS) Accreditation & Equivalency ( A & E) Program of the Department of Education (DepEd) of the Philippines in line with the K to 12 Basic Education Curriculum.

Monday, May 22, 2017

Sample als test: problem-solving & critical thinking, no comments:.

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English Practice Tests

Direction: Choose the best answer by clicking on the button of your choice.

1. You are calling your friend Jake and his father answers the phone. Which statement is appropriate for you to say? a. I want to talk to Jake not you Mr. Cruz. b. Good morning Mr. Cruz. May I speak with Jake please? c. Please give the phone to Jake. d. I need to talk to Jake Mr. Cruz.

Please make a choice.

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  8. 10 questions you have about ALS (and the answers)

    Amyotrophic Lateral Sclerosis is a rare disorder that affects the function of nerves and muscles that are responsible for voluntary muscle movement. ALS is a degenerative disease that causes the death of the nerve cells that control our muscles. It leads to progressive weakness that will spread from limb to limb to ultimately involve the entire ...

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  11. How ALS Is Diagnosed: Tests and Symptoms

    The most common test used for suspected ALS is an electromyography (EMG). This test involves sensors and an electric current placed through a needle into the muscle that looks at the signals that run between nerves and muscles. In ALS, there is a distinct pattern of electrical activity in the muscles and nerves.

  12. Practice Test On ALS! Quiz

    ALS in some cases refers to disease known as the Amyotrophic Lateral Sclerosis which leads to gradual paralyzes of people because the brain is no longer able to communicate with the muscle but this scenario is a different situation. This has got to do with a military stuff. Take this quiz and find out what is there. Questions and Answers. 1.

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    PaCO2 35 mmHg. 3. SaO2 92%. Mechanical ventilation should be started at a rate of 10 to 12 breaths per minute and adjusted as necessary to keep ETCO2 levels in the range of 35 to 40 mmHg and PaCO2 levels in the range of 40 to 45 mmHg. The minimum fraction of inspired oxygen necessary to maintain an SaO2 of at least 94% is used.

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