inflammatory breast cancer case study

This specific case is a typical controversial case because there is still disagreement over whether it can be classified as primary or secondary inflammatory breast cancer [2, 3]. Besides the clinical features present (oedema, peau d'orange, and erythema developed over a short period of 2 months) and the absence of a concrete palpable mass, no ...

Inflammatory breast cancer (IBC) is a rare subtype of locally advanced breast cancer according to the TNM breast cancer staging system. It accounts for about 2% to 4% of breast cancer cases in the United States. ... the experience of a case-control study of inflammatory breast cancer in North Africa in the past 10 years. Cancer Med. 2012 Dec; 1 ...

Inflammatory breast cancer is a rare and aggressive malignancy that is often initially misdiagnosed because of its similar presentation to more benign breast pathologies such as mastitis, resulting in treatment delays. Presenting symptoms of inflammatory breast cancer include erythema, skin changes such as peau d' orange or nipple inversion, edema, and warmth of the affected breast. The ...

Iwata H, Masuda N, Yamamoto Y, et al. Validation of the 21-gene test as a predictor of clinical response to neoadjuvant hormonal therapy for ER+, HER2-negative breast cancer: the TransNEOS study ...

Inflammatory breast cancer (IBC) is a rare and aggressive clinicopathological entity of breast cancer. It represents 1% to 6% of all cases of breast cancer [ 1 ]. The first description of IBC in the scientific literature was published in 1814 by Sir Charles Bell [ 2 ], then in 1938 the terms "true IBC" and "primary IBC" were coined to ...

The optimal radiation dose and fractionation schedule is not established for inflammatory breast cancer. In one study, 28 higher-dose radiation (66 Gy vs. 60 Gy) given by hyperfractionation (twice ...

Inflammatory breast cancer is a rare but highly aggressive form of locally advanced breast cancer. Historically, this disease was uniformly fatal; however, with the advent of induction chemotherapy and carefully coordinated multimodality treatment, the prognosis of these patients has improved. ... Azam SI, Rahbar MH: Case control study of ...

Background: Inflammation has been hypothesized to play a role in the development and progression of breast cancer and might differently impact breast cancer risk among pre and postmenopausal women. We performed a nested case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...

Clinical Presentation. Patients present with rapid onset (typically less than 3 months) of asymmetric breast enlargement accompanied by tissue thickening, erythema, induration, and warmth involving greater than one third of the breast tissue. The pathognomonic finding is dimpling of the skin known as peau d'orange, which occurs due to ...

The purpose of this study is to evaluate how well radiation therapy with or without olaparib works in treating patients with inflammatory breast cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Purpose: Inflammatory breast cancer (IBC) is a rare, poorly understood and aggressive tumor. We extended prior findings linking high body mass index (BMI) to substantial increased IBC risk by examining BMI associations before and after adjustment for well-characterized comorbidities using medical record data for diabetes, insulin resistance, and disturbances of cholesterol metabolism in a ...

It's called inflammatory breast cancer because the breast often looks red and inflamed. Most inflammatory breast cancers are invasive ductal carcinomas [ 174 ]. This means they began in the milk ducts. About 1% to 5% of breast cancers in the U.S. are inflammatory breast cancers [ 174-175 ]. Women with inflammatory breast cancer tend to be ...

Background Inflammation has been hypothesized to play a role in the development and progression of breast cancer and might differently impact breast cancer risk among pre and postmenopausal women. We performed a nested case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...

A case-control study in France showing that a pro-inflammatory diet is associated with a higher risk of breast cancer. Sci Rep. 2021;11:1-10. Article CAS Google Scholar

Case presentation. A 78-year-old male presented to the breast clinic with an abscess and was later diagnosed with inflammatory breast cancer. He presented with an abscess and was initially treated with antibiotics. Imaging showed a large left breast mass consistent with inflammatory carcinoma with axillary lymph node involvement.

Background Dermatomyositis is associated with malignant tumors including breast cancer, and inflammatory breast cancer is considered to have a poorer prognosis than most breast cancers. Case presentation A 74-year-old Asian woman, developed erythema on her face, back, and the back of her hands, 3 weeks before attending our department. At the same time, she had noticed a right breast mass and ...

Objective: We evaluated the risk factors of inflammatory breast cancer (IBC) compared to non-IBC and according to histological subtype. Methods: Cases of IBC (n = 160) and controls of non-IBC (n = 580) were collected from the cohort of breast cancer patients treated in two oncology centers matched based on age at cohort entry. Data about breast cancer risk factors were collected.

Epidemiological studies have reported associations between inflammatory skin diseases and breast cancer risk. A cohort study by Yang et al. 12 found that patients with breast cancer had a ... These outcomes underscore the intricate nexus between breast cancer and inflammatory skin conditions and the necessity of integrating various lines of ...

Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer that accounts for only a small percent of invasive breast cancers in the United States. We report a case of advanced bilateral IBC in a 60-year-old female. This case report explores the clinical presentation, pathological findings, and different imaging modalities ...

There are multiple breast cancer risk models out there. How are they different? Dr. Pfeiffer: One big difference is the [risk] factors the models consider. In addition, some take into account that a woman might die from causes other than breast cancer. NCI's risk assessment models for breast cancer, colorectal cancer, and melanoma do this.

Introduction: The putative relationship between diet, including its inflammatory potential, and breast cancer has been studied extensively, but results remain inconsistent. Using data from a large Italian case-control study conducted between 1991 and 1994, we examined the association between the dietary inflammatory index (DII) and odds of breast cancer.

Obesity is associated with one-fifth of cancer deaths, and breast cancer is one of the obesity-related cancers. Triple-negative breast cancer (TNBC) lacks estrogen and progesterone receptors and human epidermal growth factor receptor 2, leading to the absence of these therapeutic targets, followed by poor overall survival. We investigated if obesity could hasten TNBC progression and ...

Radiologic studies report that the appearances are consistent with an inflammatory left breast carcinoma and metastatic axillary lymph nodes. To complete the triple assessment, a core biopsy was done for the left breast and the axillary lymph node. ... This patient, who is now the 13th reported case of inflammatory breast cancer in men, is only ...

Breast cancer may manifest in several patterns, including the triple-negative subtype, breast Paget disease, inflammatory breast cancer, non-Hodgkin lymphoma, and soft tissue carcinoma. While a direct cause for breast cancer is yet to be established, several risk factors have been identified and closely linked to its manifestation [ 2 , 3 ].

The relationship between the inflammatory potential of diet and breast cancer has been studied extensively, but results remain inconsistent. This study aimed to investigate the association between the dietary inflammatory index (DII) and odds of breast cancer. Methods: This case-control study includes 180 women with breast cancer and 360 ...

Breast cancer (BrCA) is one of the most commonly diagnosed cancers and is the leading cause of cancer deaths in women worldwide. This study aimed to examine the association between the dietary inflammatory index (DII ®) and BrCA among Jordanian women.A total of 400 adult women were enrolled into this case-control study.

In a case that will test the U.S. Food and Drug Administration's authority to approve or reject new vaping products, the U.S. Supreme Court said Tuesday it will weigh whether the agency was ...

Lung cancer has the highest incidence rate and mortality among all malignant tumors [].As the stage of lung cancer progresses, the five-year survival rate gradually decreases [].In stage IA groups, the rates exceed 90%, while in stage IV groups, the rates are less than 10% [].Therefore, the early diagnosis of lung cancer is of great significance and can considerably improve lung cancer ...

Methods. IBC cases (n = 141) were compared to non-inflammatory breast cancer cases (n = 178) ascertained through George Washington University (GWU) with respect to the prevalence of first-degree family history of breast cancer and selected environmental/lifestyle risk factors for breast cancer.Similar comparisons were conducted with subjects from three case-control studies: breast cancer ...

Introduction: Prior research has explored the relationship between inflammatory skin disorders and breast cancer (BC), yet the causality of this association remains uncertain. Methods: Utilizing a bidirectional two-sample Mendelian randomization (MR) approach, this study aimed to elucidate the causal dynamics between various inflammatory skin conditions-namely acne, atopic dermatitis ...